Epirium Bio is developing compounds (Epicatechin) that promote mitochondrial biogenesis (the making of new mitochondria). They report the discovery of a previously unknown hormonal pathway that appears to regulate mitochondrial biogenesis. “Among the distinctive properties of this hormonal pathway is the generation of new, functional mitochondria, coupled with restoring the structure and function of previously atrophic tissue, particularly that of neuromuscular and central nervous systems. The coupling of these pathways mimics a physiological process that can be seen in response to physical exercise and that is essential for the proper functioning of organs.”

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