Elamipretide

Elamipretide is a peptide compound developed by Stealth Therapeutics. It targets the inner mitochondrial membrane where it binds reversibly to cardiolipin. In preclinical or clinical studies, elamipretide increases mitochondrial respiration improves electron transport chain function and ATP production and reduces the formation of pathogenic ROS levels. Functional benefit is achieved through enhanced ATP production and interruption and potential reversal of damaging oxidative stress.